Relationship with Humans, Habitat and Circulation

The Varicella Zoster Virus (VZV) infects humans, usually within the first decade of life. When contracted during childhood, VZV comes in a mild form (Varicella)- if the VZV is contracted during adulthood (Herpes Zoster), it can be very severe. VZV is transmitted/ circulated in/through aerosol droplets or through direct contact with secretion or broken vesicle of an infected individual. These droplets are released from skin pox in infected people. Infected people are infectious from two days before the skin rash (small red bumps on the skin all over the body) and slight fever appear, until about a week post rash appearance. This means that he habitat of the virus is the human body and survives by being passed from human to human.

VZV is a latent virus, so an individual that is infected by VZV do not show symptoms until the VZV (which resides in the ganglia to reproduce) is reactivated. When reactivated, normally one to three weeks after the initial infection, a rash appears which consists of small, itchy, red lumps/ spots that appear on the abdomen.

There is a broad spectrum of similarities and differences between Varicella (chicken pox) and Herpes Zoster (shingles) which are both contracted through the Varicella Zoster Virus. For example, Varicella occurs in childhood and is spread by aerosols and Zoster occurs during adolescence or adulthood by recurrence of latent infections. Those with active Zoster may be contagious for those around the individual and those who come in contact may develop Varicella (chicken pox). Varicella mainly affects oropharynx and skin and Zoster affects the trigeminal, cervical, thoracic, or lumbosacral dermatome. However, Varicella and Zoster are both normally nonrecurring (no reactivation); in other words, once Varicella Zoster has run its course, infected bodies grow immune. There are always exceptions: Varicella may never be contracted and Zoster’s second attacks sometimes happen but are extremely rare.

Varicella, as mentioned earlier, is predominant in children. Fortunately, Varicella is not very dangerous; treatment includes only a 1% phenol calamine cream that will prevent itching that may scar. Zoster, contrary to above, is quite dangerous and can include many complications including severe post herpetic pain (painful condition involving nerve fibers and skin), ophthalmic Zoster (involving superficial and deep injuries to the eye) and Generalized Zoster (presence of vesicles distributed along dermatome with the normal rash). Zoster normally affects immune compromised patients and elderly people who what dwindling immune systems. There are always exceptions specific to patients. For example, the usually uneventful recovery from Varicella (chicken pox) is often much more dangerous in a child with leukemia, and may develop pneumonia.

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One response to this post.

  1. Fact: If Varicella Zoster Virus infects a woman who is in her first half of pregnancy, her child may be born with severe skin scars, often accompanied by limb malformations and lesions of the eyes. If the mother gives birth to her child within 5 days of contracting VZV, the child may have severe infections and is faced with a 30% fatality rate. If it is more the 5 days, the mother would have likely developed an antibody for the virus and passed it on to her fetus, therefore making the infection much milder.

    Reply

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